The complementarity and synergistic collaboration of the INFORM project partners is also based on a large expertise and availability of biological and imaging methods:
Imaging and biophysical platforms :
Our consortium gathers a wide range of expertise in imaging and biophysical technologies, which provide the necessary tools to explore new frontiers in biology. These technologies are complementary to each other and cover a continuum of spatial and temporal scales:
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to measure speed/dynamics: spinning disk confocal microscopy, Sheet illumination microscopy (SPIM), Fluorescence Correlation Spectroscopy (FCS)
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to assess high resolution at the molecular and supramolecular level: Single molecule fluorescence Imaging/PALM, Atomic Force Microscopy (AFM), Electron Microscopy.
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to monitor interactions: AFM, FCS
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to measure forces: AFM, optical tweezers, laser nanodissection
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tor in-depth imaging: Multiphoton Microscopy
For the needs of the INFORM project we also run complementary technologies development such as PALM-SPIM, high speed AFM, and Bessel beam 3D fast microscopy.
Biology platforms:
Partners of the Labex display high expertise in down-top biological models, from cell culture to integrated in vivo models together with complete associated facilities:
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Integrated C. elegans functional genomics platform
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Drosophila melanogaster
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Immunophenomics IBISA platform (KO,Ki murine models )
